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CHEM 198 - Molecules and Medicine (Spring 2012)
Lecture: 11:00-11:50 pm, MWF in 014 Jepson (Sect.
01, CRN 20908).
Instructor: Jeff Cronk E-mail:
cronk@gonzaga.edu Office: 234 Hughes.
Office Hours: Mon, Wed 2-3 PM; Tue, Thu 10-11 AM; also by appointment
Required Text: none. Supplementary reading: "Molecules and Medicine" by E.J. Corey, B. Czako, L. Kurti (2007, Wiley, ISBN978-0-470-22749-7, paperback) |
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Class schedule: Tentative
(revision, 03-02-2012) |
MONDAY |
WEDNESDAY |
FRIDAY |
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>WEEK 1
16, 18, 20 January
( Lectures 1, 2 ) |
MLK Holiday |
18 January
Introduction
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20 January
Chemistry
fundamentals |
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WEEK
2
23, 25, 27 January
( Lectures 3, 4, 5 ) |
23 January
Covalent bonding and
noncovalent forces |
25
January
Inorganic and
organic molecules
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27
January
Drugs and their targets:
Two examples |
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WEEK
3
30 January; 1, 3 February
( Lectures 6, 7, 8 ) |
30
January
Biological molecules:
Introduction
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1 February
Biological molecules:
Carbohydrates
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3
February.
Biological molecules:
Nucleic acids |
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WEEK 4
6, 8, 10 February
( Lectures 9, 10, 11 ) |
6
February.
Biological molecules:
Lipids: fatty acids |
8
February.
Biological molecules:
Lipids and membranes
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10
February.
Lipids and membranes
Isoprenoid lipids
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WEEK 5
13, 15, 17 February
( Lectures 12, 13, 14 ) |
13
February.
Biological Molecules:
Amino acids |
15
February.
Biological molecules:
Peptides
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17
February
Protein structure:
Molecular architecture |
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WEEK 6
20, 22, 24 February
( Lectures 15, 16) |
President's
Day
Holiday |
22
February.
Proteins:
Structure and function
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24
February
Metabolism and
metabolic pathways |
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WEEK 7
27, 29 February; 2 March
( Lectures 17, 18, 19 ) |
27
February
Metabolic energy
and regulation |
29 February
Metabolic regulation:
Hormones and fuel guages
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2 March
Anti-inflammatory drugs:
Asprin and NSAIDs |
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WEEK 8
5, 7, 9 March
( Lectures 20, 21 ) |
5
March
Topics in molecular
medicine; Review
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7 March
Midterm Exam
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9
March
Topics in molecular
medicine |
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WEEK 9 -- Spring Break 12 - 16 March |
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MONDAY |
WEDNESDAY |
FRIDAY |
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WEEK 10
19, 21, 23 March
( Lectures 22, 23, 24 ) |
19 March.
Project abstracts
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21 March.
Project abstracts
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23 March
Project abstracts |
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WEEK
11
26, 28, 30 March
( Lecture 25, 26, 27) |
26
March.
Project abstracts |
28
March.
Project abstracts
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30
March.
Project abstracts |
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WEEK 12
2, 4, 6 April
( Lectures 28, 29 ) |
2
April.
Project abstracts |
4 April .
Project abstracts
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Good Friday
Holiday |
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WEEK 13
9, 11, 13 April
( Lectures 30, 31 ) |
Easter Holiday |
11
April.
Project presentations |
13 April.
Project presentations |
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WEEK 14
16, 18, 20 April
( Lecture 32, 33, 34 ) |
16 April.
Project presentations |
18 April.
Project presentations
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20 April.
Project presentations |
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WEEK 15
23, 25, 27 April
( Lectures 35, 36, 37 ) |
23 April
Project presentations |
25
April
Project presentations
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27 April
Project presentations |
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WEEK 16
30 April; 2, 4 May
( Lectures 38, 39, 40 ) |
30 April.
Project presentations |
2 May.
Presentations
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4 May.
Presentations |
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FINAL
EXAM PERIOD - Thursday 10 May
2012, 8:00 - 10:00 am: Project presentations |
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Note: The class schedule above is tentative and is subject to revision. Topics to be included in the several weeks prior to abstract presentations will vary depending on student interest. |
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Course description Chemistry aims to explain the phenomena of our everyday world in terms of the molecules that make up the substances all around us. A most fascinating aspect of chemistry concerns the molecules that make up living organisms. In this course, we will gain an appreciation of the complexity of biomolecular systems, and open a path for exploration into a broad array of biochemical accounts of human life, such as nutrition, drugs, and disease. A particular focus for this course will be some of the most important medicines that have a daily impact on our lives or those of our loved ones. A survey of some of the major therapeutic areas in medicine will be undertaken, providing a molecular understanding of important drug examples in each area. At the same time, opportunities to discuss the impact of science on society will arise, as basic and clinical research, the pharmaceutical industry, governmental agencies, and consumers represent constituencies with varying scientific, ethical, and economic agendas.
Grading: Grades will be based mostly (~75%) upon a semester project consisting of presentation of an abstract (project proposal, 5 - 10 min), project presentation (15 - 20 min), and project research paper. A smaller percentage (~25%) of each grade will be assigned on the basis of class participation and any homework, quizzes or exam administered. NOTE: It is your responsibility to be familiar
with and abide by GU's Academic Honesty Policy
Participation is important! If you do not come to class, you are not participating. Part of your grade will depend on participation, including peer reviews of project presentations. Note that we will be using the final examination period for project presentations, so plan to attend even if you are not scheduled to present.
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