Lecture 29. Regulation of glucose metabolism

Friday 18 November 2016

Regulation of glycolysis. Reactions of gluconeogenesis. Substrate cycles. Reciprocal regulation of glycolysis and gluconeogenesis.

Reading: VVP4e - Ch.15, pp.496-501; Ch.16, pp.538-545.

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Summary

The regulation of the glycolytic pathway also has a logic, one that is context-dependent. We finish our study of glycolysis with a look at some control issues. In order to fully understand the regulation of glycolysis, we must know a little bit about its alter-ego pathway, gluconeogenesis, along with general principles of metabolic regulation.